Growth Hormone Releasing Peptides or Peptides stimulating endogenous Growth Hormone secretion
Growth Hormone Releasing Peptides (GHRP-2, GHRP-6 and Hexarelin) are a small family of peptides acting at the pituitary and the hypothalamus to release Growth hormone (GH). These peptides were discovered 20 years ago and in clinical researches proved to be able to stimulate pituitary to produce endogenous Growth hormone.
GHRP-2, GHRP-6 and Hexarelin are replaceable drugs and have similar mechanism of action.
Hexarelin is considered to be the strongest peptide stimulating GH secretion. With its use, the increase in cortisol and prolactin levels is also high enough. GHRP-2 is less strong than Hexarelin, but the increase in cortisol and prolactin levels is less too. GHRP-6 is less strong than GHRP-2, but when used in dosage up to 100mcg, it has no influence on the levels of cortisol and prolactin, and in dosage more than 100mcg, the increase in cortisol and prolactin levels is modest.
Another drug stimulating endogenous GH secretion is long-acting CJC-1295 (Long-acting Growth Hormone Releasing Hormone Analog).
Common dosage regimen of Peptides:
Cycle: 16 months. The dosage is prescribed individually and injected 1-6 times a day starting with 25-50mcg and gradually increasing it with the step of 25-50mcg to achieve minimal side effects. Then, there should be return to the starting dose. The injections are usually made subcutaneously in an abdominal area 30 minutes before or in 1-1.5 after meal. The time between injections should be 3-4 hours (in order the body has the time to produce GH for further release).
Hexarelin is a peptide structurally similar to GHRP-6, which stimulates secretion of endogenous GH. Hexarelin has the majority of synthetic GH effects, but these effects are less evident with Hexarelin than with GH. The main effects of Hexarelin include increase of strength, growth of new muscle fibers, improving of vessels state, reduction of fat mass. The main difference of Hexarelin from GHRP-6 is that Hexarelin does not promote appetite, because it does not increase the level of ghrelin in the body.
This drug proved to be a great healer of wounds and can be administered as a multipurpose anabolic and with the purpose to stimulate endogenous GH secretion inhibited with the use of synthetic GH.
Medicinally, Hexarelin can be used to treat GH deficiency induced diseases.